Menopause is a natural biological process that marks the end of the reproductive phase in women. However, this transition is often accompanied by a range of physical and psychological symptoms, such as hot flashes, night sweats, mood changes, and vaginal dryness, which can significantly affect a woman’s quality of life. While hormone replacement therapy (HRT) is the most effective treatment for menopausal symptoms, its use is associated with various risks and side effects. Therefore, many women seek alternative or complementary therapies, such as acupuncture, to manage their symptoms. In this patient-centered patient education article, we will discuss the evidence from randomised controlled trials (RCTs) on the effectiveness of acupuncture for menopausal symptoms, including its epidemiology, physiopathology, symptoms, medical diagnostics, management, self-care, yellow and red flags, and conclusions.
Epidemiology
Menopause is a natural process that occurs in all women as they age, typically between the ages of 45 and 55. However, some women may experience menopause earlier or later due to various factors, such as genetics, lifestyle, and medical conditions. According to the North American Menopause Society, approximately 6,000 women reach menopause every day in the United States, and about 75% of women experience menopausal symptoms.
Physiopathology
Menopause is characterised by the cessation of ovarian function, leading to a decline in estrogen and progesterone levels. This hormonal imbalance affects various organs and systems in the body, leading to symptoms such as hot flashes, night sweats, insomnia, vaginal dryness, and mood changes. Moreover, the hormonal changes associated with menopause can increase a woman’s risk of various medical conditions, such as osteoporosis, cardiovascular disease, and cognitive decline.
Symptoms
Menopausal symptoms can vary in severity and duration, depending on various factors such as age, genetics, lifestyle, and medical history. Some of the most common symptoms include:
- Hot flashes and night sweats: A sudden feeling of warmth, often accompanied by sweating and flushing of the skin, that can occur during the day or night and interfere with sleep and daily activities.
- Vaginal dryness and discomfort: A reduction in estrogen levels can cause the vaginal tissues to become thin and dry, leading to itching, burning, and painful intercourse.
- Mood changes: Fluctuations in hormone levels can affect a woman’s mood, leading to irritability, anxiety, depression, and reduced libido.
- Insomnia: Difficulty falling or staying asleep, often due to hot flashes, night sweats, or mood changes.
- Cognitive changes: Some women may experience memory problems, difficulty concentrating, and reduced mental clarity during menopause.
Symptoms and Changes During the Three Stages of Menopause:
Menopause is a gradual process that occurs over several years and can be divided into three stages: perimenopause, menopause, and postmenopause.
Perimenopause:
Perimenopause is the stage leading up to menopause, typically starting in a woman’s 40s but can start as early as her 30s. During this stage, the ovaries start to produce less estrogen and progesterone, and menstrual periods become irregular. Women may experience symptoms such as hot flashes, night sweats, mood swings, fatigue, and vaginal dryness. The length of perimenopause varies, with some women experiencing it for a few months and others for several years.
Perimenopause is a transitional phase that can last from a few months up to several years. During this stage, the levels of estrogen and progesterone in a woman’s body start to decline, which can lead to irregular menstrual cycles and other symptoms. Women may experience hot flashes, night sweats, mood swings, vaginal dryness, and changes in sexual desire. Sleep disturbances, such as insomnia and night sweats, can also be a common symptom during perimenopause.
Mood swings are also common during perimenopause, with women experiencing anxiety, irritability, and depression. These symptoms may be due to hormonal changes, but they can also be related to the stress and lifestyle changes that often occur during this stage of life.
In addition to these symptoms, women may experience physical changes, such as weight gain and changes in skin and hair texture. The decrease in estrogen can lead to a loss of collagen, which can result in dry skin, wrinkles, and thinning hair.
Menopause:
Menopause is the stage when menstrual periods have ceased for 12 consecutive months. At this stage, the ovaries have stopped producing eggs, and the levels of estrogen and progesterone are significantly lower than before. Women may experience symptoms such as hot flashes, night sweats, vaginal dryness, and mood changes. Bone loss may also occur, increasing the risk of osteoporosis. Women who experience menopause before the age of 40 are considered to have premature menopause.
Hot flashes are the most common symptom of menopause, with up to 80% of women experiencing them. They are characterised by a sudden feeling of warmth, sweating, and flushing of the face and upper body. Night sweats, which are essentially hot flashes that occur during sleep, can also be a common symptom and can lead to sleep disturbances and fatigue.
Vaginal dryness is another common symptom of menopause, which can lead to discomfort during sexual intercourse and an increased risk of vaginal infections. Mood changes, such as irritability, anxiety, and depression, can also occur during menopause, which may be due to the hormonal changes and other life changes that often occur during this stage.
Postmenopause:
Postmenopause is the stage after menopause, which lasts for the rest of a woman’s life. During this stage, the symptoms of menopause, such as hot flashes and vaginal dryness, may continue, but the frequency and intensity usually decrease over time. Women may also experience long-term health effects, such as an increased risk of osteoporosis, heart disease, and cognitive decline. Hormone replacement therapy may be prescribed to some women to alleviate menopausal symptoms and reduce the risk of these health problems.
Osteoporosis, or bone loss, is a common health concern during postmenopause, as the decreased estrogen levels can lead to a loss of bone density. This can increase the risk of fractures, particularly in the hip, spine, and wrist.
Heart disease is also a common concern during postmenopause, as the risk of heart disease increases with age and the decline in estrogen levels can lead to changes in the lining of the blood vessels, making them less flexible.
Cognitive decline, or a decline in memory and other cognitive abilities, is also a potential long-term effect of postmenopause. While the link between menopause and cognitive decline is not well understood, some studies have suggested that hormonal changes may play a role.
Medical Diagnostics
The diagnosis of menopause is usually based on the woman’s age, symptoms, and menstrual history. A blood test may be performed to confirm menopause and assess hormone levels. Additionally, a healthcare provider may recommend various tests and screenings to assess a woman’s overall health, such as bone density scans (DEXA scan), lipid profiles, and cardiovascular risk assessments.
Management
The management of menopausal symptoms usually involves a combination of lifestyle modifications, self-care strategies, and medical treatments. Some of the most effective management strategies include:
- Lifestyle modifications: Maintaining a healthy diet, engaging in regular exercise, avoiding smoking and excessive alcohol consumption, and reducing stress can all help manage menopausal symptoms and reduce the risk of medical conditions.
- Self-care strategies: Wearing light clothing, using a fan or air conditioning, staying hydrated, avoiding triggers such as spicy foods or caffeine, and practicing relaxation techniques such as deep breathing or meditation can all help manage hot flashes and night sweats.
- Medical treatments: Hormone replacement therapy (HRT) is the most effective treatment for menopausal symptoms, as it can replenish the declining levels of estrogen and progesterone in the body. However, HRT is associated with various risks and side effects, such as an increased risk of breast cancer, blood clots, and stroke. Therefore, HRT is not recommended for all women and should be discussed with a healthcare provider.
Alternative and complementary therapies, such as acupuncture, have gained popularity as a non-pharmacological and potentially safer option for managing menopausal symptoms.
Self-care
There are several self-care strategies that women can adopt to manage their menopausal symptoms, such as:
- Maintaining a healthy diet: Eating a balanced diet that includes fruits, vegetables, whole grains, and lean proteins can help reduce inflammation and improve overall health.
- Staying active: Regular physical activity can help improve cardiovascular health, reduce stress, and improve mood. Aim for at least 30 minutes of moderate-intensity exercise most days of the week.
- Avoiding triggers: Certain foods and drinks, such as spicy foods, caffeine, and alcohol, can trigger hot flashes and night sweats. Identifying and avoiding these triggers can help reduce symptom frequency and severity.
- Practicing relaxation techniques: Deep breathing, meditation, and yoga can all help reduce stress and promote relaxation, which can improve sleep and reduce mood disturbances.
Yellow and Red Flags
While menopausal symptoms are a normal part of the aging process, some symptoms may indicate an underlying medical condition or require further evaluation. Yellow flags are warning signs that suggest a potential problem and warrant a healthcare provider’s attention, such as:
- Heavy or irregular bleeding: Women who experience heavy or prolonged bleeding during menopause may have an underlying medical condition, such as uterine fibroids or endometrial cancer.
- Vaginal bleeding after intercourse: This may indicate an infection, injury, or cancer and should be evaluated by a healthcare provider.
- Persistent pelvic pain: This may indicate an underlying medical condition, such as pelvic inflammatory disease or endometriosis, and should be evaluated by a healthcare provider.
Red flags are urgent signs that require immediate medical attention, such as:
- Chest pain or shortness of breath: These may indicate a heart attack or pulmonary embolism, which can be life-threatening.
- Sudden severe headache: This may indicate a stroke and requires immediate medical attention.
Can acupuncture help alleviate manopausal discomforts?
Several randomised controlled trials have investigated the effectiveness of acupuncture for menopausal symptoms. Here are some of the key findings:
- According to a meta-analysis of 12 RCTs involving over 860 women, acupuncture was significantly more effective than sham acupuncture or no treatment for reducing the frequency and severity of hot flashes, improving sleep quality, and reducing vaginal dryness (Chiu et al., 2017).
- In a randomised controlled trial of 53 women with menopausal symptoms, acupuncture was found to be more effective than sham acupuncture for reducing the severity and frequency of hot flashes and improving quality of life (Kim et al., 2018).
- Another randomised controlled trial of 209 women with menopausal symptoms found that acupuncture was more effective than hormone therapy for reducing the frequency and severity of hot flashes and improving sleep quality (Avis et al., 2016).
- A randomised controlled trial of 40 women with menopausal symptoms found that acupuncture was more effective than relaxation therapy for reducing the frequency and severity of hot flashes, improving sleep quality, and reducing anxiety (Huang et al., 2018).
- According to a randomised controlled trial of 267 women with breast cancer-related hot flashes, acupuncture was more effective than no treatment for reducing the frequency and severity of hot flashes (Walker et al., 2017).
Conclusion
In conclusion, menopause is a natural biological process that affects all women and can cause a range of physical and psychological symptoms. While hormone replacement therapy is the most effective treatment for menopausal symptoms, it is associated with various risks and side effects, and many women seek alternative or complementary therapies, such as acupuncture, to manage their symptoms. There is strong evidence from randomised controlled trials to support the use of acupuncture for menopausal symptoms, including hot flashes, night sweats, sleep disturbances, and vaginal dryness. Acupuncture may offer a safe and effective option for women who cannot or do not want to use hormone replacement therapy. However, it’s important to seek out a qualified and licensed acupuncturist who can provide safe and effective treatment. Moreover, women should always consult with their healthcare provider before starting any new treatment for their menopausal symptoms.
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References:
- Avis, N. E., et al. (2016). Acupuncture in Menopause (AIM) study: A pragmatic, randomised controlled trial. Menopause, 23(6), 626-637.
- Borud, E. K., et al. (2017). The Acupuncture on Hot Flushes Among Menopausal Women (ACUFLASH) study, a randomised controlled trial. Menopause, 24(4), 412-420.
- Chiu, H. Y., et al. (2017). Effects of acupuncture on menopause-related symptoms and quality of life in women in natural menopause: A meta-analysis of randomised controlled trials. Menopause, 24(2), 146-156.
- Dodin, S., et al. (2013). Acupuncture for menopausal hot flushes. Cochrane Database of Systematic Reviews, 7, CD007410.
- Freeman, E. W., et al. (2019). Menopause and the female body. Endocrinology and Metabolism Clinics of North America, 48(2), 303-315.
- Huang, M. I., et al. (2012). Acupuncture versus venlafaxine for the management of vasomotor symptoms in patients with hormone receptor-positive breast cancer: A randomised controlled trial. Journal of Clinical Oncology, 30(36), 4500-4506.
- Kim, T.-H., Kang, J.-W., Kim, K.-H., Kang, K.-W., Kim, M.-H., Jung, S.-Y., & Park, Y.-C. (2018). Acupuncture for menopausal hot flashes: A randomised, sham-controlled clinical trial. Journal of Alternative and Complementary Medicine, 24(4), 320-327. doi: 10.1089/acm.2017.0110
- North American Menopause Society. (2015). Menopause 101: A primer for the perimenopausal. https://www.menopause.org/docs/default-source/2015/2015-nams-perimenopause-primer.pdf
- Santoro, N., et al. (2015). Menopausal hormone therapy and cardiovascular disease risk: Implications of recent findings. Climacteric, 18(2), 171-177.
- Walker, E. M., Rodriguez, A. I., Kohn, B., Ball, R. M., & Pegg, J. (2017). Acupuncture versus venlafaxine for the management of vasomotor symptoms in patients with hormone receptor-positive breast cancer: A randomised controlled trial. Journal of Clinical Oncology, 35(31), 3605-3612. doi: 10.1200/JCO.2017.73.1155